Pharmacology is presumed to involve mixed monoamine reuptake inhibition and releasing action with NET≈DAT>SERT, similar to 4-MEC but slightly less potent and longer lasting due to the ethyl para-substitution. Limited formal toxicology data exists; acute risks mirror other cathinones including tachycardia, hypertension, hyperthermia, vasoconstriction, bruxism, and potential serotonin syndrome when mixed with serotonergics. Hydration, temperature monitoring, and magnesium supplementation for jaw tension are advisable. Avoid consecutive-day use. Very little peer-reviewed data exists; all dosage and duration figures are extrapolated from seizure reports and small user samples—start with low doses.
Also known as: 4-ethylethcathinone, 4‑Ethyl‑N‑ethylcathinone, Para‑ethyl ethcathinone, P‑ethyl ethcathinone
Classification
Chemical: Cathinone
Psychoactive: Entactogen
Psychoactive: Stimulant
Tag: Research-Chemical
Effects
Stimulation
Physical Euphoria
Teeth Grinding
Vasoconstriction
Pupil Dilation
Increased Heart Rate
Cognitive Euphoria
Empathy Affection And Sociability Enhancement
Thought Acceleration
Motivation Enhancement
Focus Enhancement
Compulsive Redosing
Increased Libido
Appetite Suppression
Dehydration
Increased Music Appreciation
Open Eye Visuals
Light Sensitivity
Routes of Administration
Oral
Dosage
Threshold: 40 mg
Light: 75 – 125 mg
Common: 125 – 250 mg
Strong: 250 – 350 mg
Heavy: 350 mg +
Duration
Onset: 0.17-0.5 h
Comeup: 0.33-0.67 h
Peak: 1-3 h
Offset: 1-2 h
After Effects: 2-24 h
Total Duration: 4-7 h
Insufflated
Dosage
Threshold: 15 mg
Light: 30 – 60 mg
Common: 60 – 120 mg
Strong: 120 – 200 mg
Heavy: 200 mg +
Duration
Onset: 0.02-0.08 h
Comeup: 0.08-0.25 h
Peak: 0.25-1 h
Offset: 1-2 h
After Effects: 2-24 h
Total Duration: 3-6 h
Rectal
Dosage
Threshold: 30 mg
Light: 60 – 100 mg
Common: 100 – 180 mg
Strong: 180 – 250 mg
Heavy: 250 mg +
Duration
Onset: 0.08-0.25 h
Comeup: 0.25-0.5 h
Peak: 0.75-2.5 h
Offset: 2.5-5 h
After Effects: 2-24 h
Total Duration: 4-7 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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4-EEC - دليل المواد DrugsPRO
4-EEC: Pharmacology is presumed to involve mixed monoamine reuptake inhibition and releasing action with NET≈DAT>SERT, similar to 4-MEC but slightly less potent and longer lasting due to the ethyl para-substitution. Limited formal toxicology data exists; acute risks mirror other cathinones including