كلورديازيبوكسيد

Chlordiazepoxide was the first benzodiazepine synthesized and is primarily prescribed for anxiety disorders and acute alcohol withdrawal. It has a long half-life and produces long-lasting active metabolites, making it useful for tapering but inappropriate for elderly patients due to accumulation risk. Abrupt discontinuation after prolonged use can cause life-threatening withdrawal including seizures. Always taper gradually under medical supervision.

Also known as: Seren, Mitran, Librium, Clindex, Tropium, CDP, Chlordiazepoxidum, Chloradiazepoxide, Clopoxide

Classification

Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Sedative

Effects

Sedation
Muscle Relaxation
Anxiolytic
Sedative
Dystaxia
Hypnotic
Anxiety Suppression
Amnesia
Thought Deceleration
Motor Control Loss
Emotion Suppression
Delusions Of Sobriety
Disinhibition
Dulled Perception

Routes of Administration

Oral

Dosage

Threshold: 2 mg
Light: 5-10 mg
Common: 10-25 mg
Strong: 25-50 mg
Heavy: 50+ mg

Duration

Onset: 0.5-1 h
Comeup: 0.5-1.5 h
Peak: 1-4 h
Offset: 12-48 h
After Effects: 12-24 h
Total Duration: 12-48 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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