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Thiopropamine (TPA) is a synthetic stimulant and research chemical structurally related to methiopropamine (MPA), differing from amphetamine by the substitution of a thiophene ring for the phenyl ring. First synthesized in 1942, it did not emerge on recreational markets until early 2016, appearing shortly after MPA was banned in the UK. It is estimated to be roughly one-third the potency of amphetamine and produces amphetamine-like stimulant effects.

Also known as: Tpa, Normethiopropamine, A-methyl-2-thipheneethanamine

Classification

Psychoactive: Stimulant
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Thiophene

Effects

Stimulation
Increased Heart Rate
Spontaneous Tactile Sensations
Increased Perspiration
Teeth Grinding
Temperature Regulation Suppression
Euphoria
Empathy Enhancement
Talkativeness
Alertness Enhancement
Focus Enhancement
Cognitive Euphoria
Increased Libido
Light Sensitivity
Appetite Suppression
Sexual Arousal

Routes of Administration

Oral

Dosage

Heavy: 125 mg
Light: 20 – 50 mg
Common: 50 – 100 mg
Strong: 100 – 125 mg
Threshold: 20 mg

Duration

No data available for this section yet.

Insufflated

Dosage

No data available for this section yet.

Duration

Onset: 0.08 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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