Library
25P-NBOMe
Extremely potent compound active in the low hundreds of micrograms range. Small measurement errors can create dangerous multi-fold overdoses. Reports of intense vasoconstriction, tachycardia, hypertension, agitation, and seizures at high doses, with multiple documented fatalities in the NBOMe series. Always conduct allergy tests with sub-threshold doses (under 50 ug) and use accurate 0.001 mg scales with volumetric dosing. Limited human pharmacological data exists; no controlled clinical trials have been published.
Also known as: Nbome-2c-p, 25P, P‑NBOMe
Classification
- Chemical: Phenethylamine
- Psychoactive: Psychedelic
- Tag: Hallucinogen
- Tag: Research-Chemical
- Tag: Tentative
Effects
- Body Temperature Fluctuations
- Stimulation
- Vasoconstriction
- Nausea
- Mouth Numbing
- Mentalphysical Stimulation
- Euphoria
- Mania
- Thought Acceleration
- Thought Connectivity
- Anxiety
- Paranoia
- Visual Patterning
- Color Enhancement
- Color Shifting
- Spatial Depth Distortion
- Tactile Enhancement
- Tactile Suppression
Routes of Administration
Sublingual
Dosage
- Threshold: 50-100 ug
- Light: 100-250 ug
- Common: 250-600 ug
- Strong: 600-900 ug
- Heavy: 900+ µg
Duration
- Onset: 0.17-0.5 h
- Comeup: 0.5-1 h
- Peak: 2-5 h
- Offset: 4-8 h
- After Effects: 2-6 h
- Total Duration: 8-14 h
Insufflated
Dosage
- Threshold: 25-50 ug
- Light: 50-120 ug
- Common: 120-300 ug
- Strong: 300-450 ug
- Heavy: 450+ µg
Duration
- Onset: 0.03-0.17 h
- Comeup: 0.25-0.5 h
- Peak: 1.5-4 h
- Offset: 4-8 h
- After Effects: 2-6 h
- Total Duration: 6-12 h
Vaporized
Dosage
- Threshold: 20-40 ug
- Light: 40-80 ug
- Common: 80-200 ug
- Strong: 200-300 ug
- Heavy: 300+ µg
Duration
- Onset: 0.03-0.08 h
- Comeup: 0.17-0.33 h
- Peak: 2-5 h
- Offset: 4-8 h
- After Effects: 2-6 h
- Total Duration: 6-12 h
Oral
Dosage
- Common: 450-700 ug
- Light: 250-450 ug
- Strong: 700-1500 ug
- Threshold: 100-250 ug
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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