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Флуразепам

Flurazepam is a long-acting benzodiazepine hypnotic prescribed for insomnia. Its active metabolite N-desalkylflurazepam has an exceptionally long half-life (40-250 hours), causing next-day sedation, cognitive impairment, and increased fall risk, especially in elderly users. Tolerance develops within 2-4 weeks of regular use. Withdrawal requires careful medical supervision with gradual dose tapering. Schedule IV controlled substance in the US.

Флуразепам molecular structure
Флуразепам molecular structure diagram from the DrugsPRO substance library.

Also known as: Dalmane, Dalmadorm, Felison, Flunox, Sompan, Valdorm, Ro 5-6901

Classification

  • Chemical: Benzodiazepine
  • Psychoactive: Depressant
  • Tag: Anxiolytic
  • Tag: GABAergic
  • Tag: Habit-Forming
  • Tag: Muscle Relaxant
  • Tag: Sedative

Effects

  • Sedation
  • Muscle Relaxation
  • Physical Euphoria
  • Residual Sleepiness
  • Anxiolytic
  • Sedative
  • Anxiety Suppression
  • Memory Suppression
  • Thought Deceleration
  • Emotion Suppression
  • Dizziness
  • Cognitive Impairment
  • Disinhibition
  • Dulled Perception

Routes of Administration

Oral

Dosage

  • Threshold: 5 mg
  • Light: 7.5-15 mg
  • Common: 15-30 mg
  • Strong: 30-60 mg
  • Heavy: 60+ mg

Duration

  • Onset: 0.25-0.75 h
  • Comeup: 0.5-1 h
  • Peak: 1-2 h
  • Offset: 8-12 h
  • After Effects: 24-48 h
  • Total Duration: 10-16 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Flurazepam - DrugsPRO ръководство за вещества

Flurazepam: Flurazepam is a long-acting benzodiazepine hypnotic prescribed for insomnia. Its active metabolite N-desalkylflurazepam has an exceptionally long half-life (40-250 hours), causing next-day sedation, cognitive impairment, and increased fall risk, especially in elderly users. Tolerance dev

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