A relatively rare dissociative anesthetic, pharmacologically classified as an NMDA receptor antagonist. It is related to other anesthetics in this family such as Ketamine and phencyclidine. Has been used to cut Ketamine, in which case it may cause additional nausea. In Veterinary practice it is mixed with Zolazolam, a potent anaesthetic at a 1:1 ratio.
Тилетамин molecular structure diagram from the DrugsPRO substance library.
Also known as: Телозол, Zoletic, Tiletaminum
Classification
Psychoactive: Depressant
Psychoactive: Dissociative
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Tentative
Effects
Somatic Lightness
Incoordination
Pain Relief
Physical Discomfort
Fatigue
Immobility
Dissociation
Euphoria
Memory Impairment
Time Dilation
Decreased Focus
Dizziness
Internal Auditory Phenomena
Dulled Perception
Auditory Distortion
Closed Eye Visuals
Open Eye Visuals
Warping
Routes of Administration
Intramuscular
Dosage
Common: 5-10 mg
Light: 2.5-5 mg
Strong: 10-20 mg
Heavy: 20 mg+
Threshold: 2 mg
Duration
Onset: 0.03-0.08 h
Peak: 0.5-1 h
Offset: 1.5-2.5 h
After Effects: 4-24 h
Total Duration: 2-4 h
Oral
Dosage
Common: 25-50 mg
Light: 10-25 mg
Strong: 50-100 mg
Heavy: 100+ mg
Threshold: 5 mg
Duration
Onset: 0.25-0.5 h
Peak: 0.75-1.5 h
Offset: 2-3 h
After Effects: 4-24 h
Total Duration: 2.5-5 h
Sublingual
Dosage
Heavy: 40 mg+
Light: 5–12 mg
Common: 12–25 mg
Strong: 25–40 mg
Threshold: 5 mg
Duration
No data available for this section yet.
Insufflated
Dosage
Heavy: 35 mg+
Light: 2–7 mg
Common: 7–20 mg
Strong: 20–35 mg
Threshold: 2 mg
Duration
Onset: 0.08-0.17 h
Peak: 0.5-1 h
Offset: 1.5-2.5 h
After Effects: 4-24 h
Total Duration: 2-4 h
Rectal
Dosage
Heavy: 40 mg+
Light: 5–15 mg
Common: 15–25 mg
Strong: 25–40 mg
Threshold: 5 mg
Duration
Onset: 0.08-0.25 h
Peak: 0.5-1 h
Offset: 1.5-2.5 h
After Effects: 4-24 h
Total Duration: 2-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Tiletamine - DrugsPRO ръководство за вещества
Tiletamine: A relatively rare dissociative anesthetic, pharmacologically classified as an NMDA receptor antagonist. It is related to other anesthetics in this family such as Ketamine and phencyclidine. Has been used to cut Ketamine, in which case it may cause additional nausea. In Veterinary practic
