1,4-DMAA

1,4-DMAA is a positional isomer of 1,3-DMAA with limited human safety data. Anecdotal reports suggest it produces smoother stimulation with enhanced mood elevation compared to 1,3-DMAA. It raises heart rate and blood pressure, causes vasoconstriction, and can precipitate serious cardiovascular events including tachyarrhythmias and intracranial hemorrhage at high doses or in susceptible individuals. Found in dietary supplements at doses ranging from 21-94 mg per serving. The FDA considers products containing 1,4-DMAA to be illegal dietary supplements.

Also known as: 1,4-dimethylamylamine, 5-methylhexan-2-amine

Classification

Psychoactive: Stimulant
Tag: Alkyl amine
Tag: Research-Chemical

Effects

Stimulation
Increased Heart Rate
Increased Perspiration
Vasoconstriction
Teeth Grinding
Restlessness
Focus Enhancement
Motivation Enhancement
Euphoria
Anxiety
Irritability
Increased Sociability
Appetite Suppression
Light Sensitivity
Increased Libido

Routes of Administration

Oral

Dosage

Threshold: 5-10 mg
Light: 10-25 mg
Common: 25-50 mg
Strong: 50-75 mg
Heavy: 75 mg

Duration

Onset: 0.25-0.75 h
Comeup: 0.5-1 h
Peak: 0.75 h
Offset: 2-3 h
After Effects: 2-6 h

Insufflated

Dosage

Threshold: 5 mg
Light: 5-15 mg
Common: 15-30 mg
Strong: 30-50 mg
Heavy: 50 mg

Duration

Onset: 0.08-0.25 h
Comeup: 0.25-0.5 h
Peak: 0.75 h
Offset: 2-3 h
After Effects: 2-6 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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