AMT is a synthetic psychedelic, stimulant, and entactogen of the tryptamine class. Originally developed by Upjohn in the 1960s, it was briefly prescribed as an antidepressant in the Soviet Union before being discontinued. Its effects are often described as a cross between classical psychedelics and MDMA, combining perceptual alterations with empathogenic and stimulant qualities. It also possesses weak, reversible monoamine oxidase inhibitor (MAOI) activity.
aMT molecular structure diagram from the DrugsPRO substance library.
Also known as: 3-it, It-290, It-403, Monase, Indopan, U-14,164E, Α-methyltryptamine
Classification
Chemical: Tryptamine
Psychoactive: Entactogen
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Research-Chemical
Tag: substituted tryptamine
Effects
Spontaneous Tactile Sensations
Stimulation
Nausea
Difficulty Urinating
Headache
Mentalphysical Stimulation
Introspection
Euphoria
Conceptual Thinking
Ego Suppression Loss And Death
Time Distortion
Enhanced Pattern Recognition
Hallucinations
Visual Drifting
Tracers
After Images
Color Shifting
Scenery Slicing
Routes of Administration
Oral
Dosage
Heavy: 60 – 80 mg
Light: 10 – 25 mg
Common: 25 – 40 mg
Strong: 40 – 60 mg
Threshold: 5-15 mg
Duration
Onset: 1-3 h
Comeup: 0.5-1.5 h
Peak: 4-6 h
Offset: 3-5 h
After Effects: 10-19 h
Total Duration: 10-14 h
Smoked
Dosage
Light: 2 – 5 mg
Common: 5 – 10 mg
Strong: 10 – 20 mg
Threshold: ~2 mg
Heavy: 20+ mg
Duration
Onset: 0-0.5 h
Insufflated
Dosage
Heavy: 40+ mg
Light: 5-15 mg
Common: 15-30 mg
Strong: 30-40 mg
Threshold: 2-5 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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aMT - DrugsPRO průvodce látkou
aMT: AMT is a synthetic psychedelic, stimulant, and entactogen of the tryptamine class. Originally developed by Upjohn in the 1960s, it was briefly prescribed as an antidepressant in the Soviet Union before being discontinued. Its effects are often described as a cross between classical psychedelics
