GHB

GHB is a depressant that occurs naturally in the human body. First synthesized in the 1920s, it has seen varied use as an anesthetic, a bodybuilding supplement, and eventually a recreational club drug by the late 1990s. It is known for producing euphoric, disinhibiting, and sedative effects. GHB carries notable risks due to inconsistent concentrations in commonly sold liquid form and dangerous interactions with other depressants.

GHB molecular structure diagram from the DrugsPRO substance library.

Also known as: G, Xyrem, Sodium oxybate, Xyrem, alcover

Classification

Chemical: GHB analogue
Psychoactive: Depressant
Tag: Butyric acid
Tag: Common
Tag: GABA analogue
Tag: GABAergic
Tag: Habit-Forming
Tag: Γ-Hydroxy acid
Tag: Sedative

Effects

Stimulation And Sedation
Respiratory Depression
Nausea
Sedation
Muscle Relaxation
Physical Fatigue
Empathy Love And Sociability Enhancement
Information Processing Suppression
Thought Deceleration
Amnesia
Euphoria
Anxiety Suppression
Disinhibition
Dehydration
Dulled Perception
Increased Libido
Open Eye Visuals
Voices

Routes of Administration

Oral

Dosage

Heavy: 3.5-5 g
Light: 0.5-1 g
Common: 1-2.5 g
Strong: 2.5-4 g
Threshold: 0.5 g
Dangerous: 7 g

Duration

Onset: 0.33-1 h
Comeup: 0.2-0.3 h
Peak: 0.8-1.5 h
Offset: 0.2-0.5 h
After Effects: 2-4 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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GHB