Remifentanil

Standard anesthetic practice uses continuous infusions of 0.05-0.25 ug/kg/min; analgesia ceases within approximately 5 minutes of pump stoppage due to ester hydrolysis. Context-sensitive half-life is 2-4 minutes regardless of infusion length. Bolus dosing outside monitored settings is strongly discouraged because apnea can occur before the syringe is empty. Remifentanil is a metabolic soft drug rapidly hydrolyzed by nonspecific tissue and plasma esterases.

Also known as: Ultiva, Remifentanyl

Classification

Chemical: Anilidopiperidine
Chemical: Opioid
Psychoactive: Depressant
Tag: Anilinopiperidine
Tag: Habit-Forming
Tag: Sedative

Effects

Physical Euphoria
Pain Relief
Sedation
Respiratory Depression
Itchiness
Bodily Control Impairment
Cognitive Euphoria
Physical Autonomy
Euphoria
Sadness
Anxiety Suppression
Compulsive Redosing
Dulled Perception
Open Eye Visuals
Sound Dampening

Routes of Administration

Intravenous

Dosage

Threshold: 5-10 ug (slow IV push)
Light: 10-20 ug
Common: 20-50 ug
Strong: 50-100 ug
Heavy: 100 µg+ (dangerous)

Duration

Onset: 0.01-0.02 h
Peak: 0.02-0.03 h
Offset: 0.05-0.08 h
After Effects: 0.08-0.25 h
Total Duration: 5-10 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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