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Sirolimus

Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa). It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It is a mammalian target of rapamycin (mTOR) kinase inhibitor that reduces the sensitivity of T cells and B cells to interleukin-2 (IL-2), inhibiting their activity.

Sirolimus molecular structure
Sirolimus molecular structure diagram from the DrugsPRO substance library.

Also known as: Rapamycin

Classification

  • Chemical: Medicine
  • Tag: Pharmaceutical

Effects

No data available for this section yet.

Routes of Administration

No route information available yet.

Harm Reduction

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Sources

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Links

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Sirolimus - DrugsPRO průvodce látkou

Sirolimus: Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumo

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