Library

2-MeO-Ketamin

Very limited formal pharmacology or toxicology data exists. Potency appears roughly comparable to racemic ketamine but with a steeper dose-response curve and slightly shorter duration. Users report it is smoother intranasally and considerably more active orally than ketamine, suggesting higher oral bioavailability. High doses can produce full anesthesia and complete dissociation (hole experience). Harm reduction: always confirm identity with reagent tests .

Also known as: Dinoket, Methoxyketamine, 2-meo-2-deschloroketamine, O‑methoxyketamine, 2‑MeO‑K

Classification

  • Chemical: Arylcyclohexylamine
  • Psychoactive: Dissociative
  • Tag: Habit-Forming
  • Tag: Hallucinogen
  • Tag: Research-Chemical

Effects

  • Pain Relief
  • Nausea
  • Numbness
  • Incoordination
  • Impaired Balance
  • Sedation
  • Physical Autonomy
  • Motor Control Loss
  • Time Distortion
  • Euphoria
  • Thought Disorganization
  • Depersonalization
  • Tactile Suppression
  • Spatial Disorientation
  • Double Vision
  • Visual Disconnection
  • Internal Hallucination
  • Cognitive Dysphoria

Routes of Administration

Insufflated

Dosage

  • Threshold: 15-25 mg
  • Light: 30-75 mg
  • Common: 75-200 mg
  • Strong: 130-200 mg
  • Heavy: 400+ mg

Duration

  • Onset: 0.08-0.17 h
  • Comeup: 0.17-0.33 h
  • Peak: 0.33-1 h
  • Offset: 60-120 h
  • After Effects: 60-240 h
  • Total Duration: 60-150 h

Oral

Dosage

  • Threshold: 20-30 mg
  • Light: 40-80 mg
  • Common: 80-200 mg
  • Strong: 200-350 mg
  • Heavy: 350+ mg

Duration

  • Onset: 0.33-0.67 h
  • Comeup: 0.33-0.67 h
  • Peak: 0.33-1 h
  • Offset: 60-120 h
  • After Effects: 120-240 h
  • Total Duration: 90-180 h

Intramuscular

Dosage

  • Threshold: 10 mg
  • Light: 20-40 mg
  • Common: 40-75 mg
  • Strong: 75-125 mg
  • Heavy: 125+ mg

Duration

  • Onset: 0.03-0.08 h
  • Comeup: 0.08-0.17 h
  • Peak: 0.33-1 h
  • Offset: 0.5-1 h
  • After Effects: 60-240 h
  • Total Duration: 60-150 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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2-MeO-Ketamine - DrugsPRO substansvejledning

2-MeO-Ketamine: Very limited formal pharmacology or toxicology data exists. Potency appears roughly comparable to racemic ketamine but with a steeper dose-response curve and slightly shorter duration. Users report it is smoother intranasally and considerably more active orally than ketamine, suggest

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