Library
ADB-PINACA
ADB-PINACA is a positional isomer of Schedule I synthetic cannabinoids; potency at CB1 is in the sub-nanomolar range (EC50 = 0.52 nM), approximately 3-6 times more potent than THC. Extremely narrow safety margin – milligram-scale errors have produced seizures, severe tachycardia, and fatalities. Always weigh with a 0.001 g (1 mg) readability scale and apply evenly to an inert herbal carrier; avoid 'eye-balling' liquid drops. Significant number of hospitalizations (Colorado 2013 outbreak, CDC) and several confirmed deaths have been attributed to ADB-PINACA or its isomers. Metabolized primarily via hepatic CYP3A4/2C9; inhibitors (ketoconazole, fluconazole, grapefruit) may prolong and intensify effects.
Also known as: Isomer 1
Classification
- Chemical: Cannabinoid
- Tag: Habit-Forming
- Tag: Hallucinogen
- Tag: Indazolecarboxamide
- Tag: Research-Chemical
Effects
- Rapid Intoxication And Body Load
- Body Heaviness And Motor Incoordination
- Dry Mouth And Red Eyes
- Tachycardia And Palpitations
- Nauseavomiting
- Cataleptic Episodes At High Doses
- Intense Euphoria Or Dysphoria
- Altered Time Perception
- Shortterm Memory Impairment
- Time Distortion
- Anxiety
- Paranoia
- Auditory And Visual Distortions
- Open Eye Visuals
- Closed Eye Visuals
- Closedeye Visuals
- Closedeye Imagery
- Visual Snow
Routes of Administration
Smoked
Dosage
- Threshold: <0.5 mg (applied to plant material or concentrate)
- Light: 0.5-1 mg
- Common: 1-2 mg
- Strong: 2-4 mg
- Heavy: >4 mg
Duration
- Onset: 0.01-0.03 h
- Peak: 0.08-0.5 h
- Offset: 1-2 h
- After Effects: 6-24 h
Oral
Dosage
- Threshold: ≈1 mg
- Light: 1-2 mg
- Common: 2-3 mg
- Strong: 3-5 mg
- Heavy: >5 mg
Duration
- Onset: 0.25-0.75 h
- Peak: 0.5-1.5 h
- Offset: 2-3 h
- After Effects: 6-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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