CBN is produced by oxidative degradation of delta-9-THC and is usually present in aged cannabis or as an isolate in commercial sleep products. It is mildly psychoactive at very high doses (approximately 25% of THC's CB1 affinity) but produces measurable sedation, muscle relaxation and mild analgesia at typical doses. Oral bioavailability is low (6-10%); high-fat meals increase absorption. CBN is metabolized by CYP2C9 and CYP3A4 enzymes to 11-OH-CBN (2x as potent as CBN). Avoid driving or operating machinery after dosing.
CBN molecular structure diagram from the DrugsPRO substance library.
Also known as: Cannabinol, Sleepy cannabinoid
Classification
Chemical: Cannabinoid
Tag: Phytocannabinoid
Tag: Sedative
Effects
Sedation
Physical Relaxation
Anxiolysis
Mild Analgesia
Reduced Muscle Tension
Appetite Stimulation
Mild Dizziness At Higher Doses
Subtle Mood Lift
Drowsiness
Anxiety Suppression
Increased Appetite
Dizziness
Dulled Perception
Routes of Administration
Oral
Dosage
Threshold: 1 mg
Light: 2 – 5 mg
Common: 5 – 20 mg
Strong: 20 – 40 mg
Heavy: 40 mg +
Duration
Onset: 0.5-1.5 h
Comeup: 0.5-1 h
Peak: 1-3 h
Offset: 2-4 h
After Effects: 2-6 h
Total Duration: 4-8 h
Sublingual
Dosage
Threshold: 1 mg
Light: 2 – 4 mg
Common: 4 – 15 mg
Strong: 15 – 30 mg
Heavy: 30 mg +
Duration
Onset: 0.25-0.75 h
Comeup: 0.33-0.67 h
Peak: 0.75-2 h
Offset: 2-4 h
After Effects: 2-6 h
Total Duration: 3-6 h
Vaporized
Dosage
Threshold: <1 mg
Light: 1 – 3 mg
Common: 3 – 10 mg
Strong: 10 – 20 mg
Heavy: 20 mg +
Duration
Onset: 0.02-0.08 h
Comeup: 0.08-0.25 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 2-6 h
Total Duration: 2-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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CBN - DrugsPRO substansvejledning
CBN: CBN is produced by oxidative degradation of delta-9-THC and is usually present in aged cannabis or as an isolate in commercial sleep products. It is mildly psychoactive at very high doses (approximately 25% of THC's CB1 affinity) but produces measurable sedation, muscle relaxation and mild anal
