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Flutoprazepam

Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life), which causes significant accumulation and next-day sedation. Due to the long half-life, effects may not peak until many hours after administration. Has been reported as a date rape drug.

Flutoprazepam molecular structure
Flutoprazepam molecular structure diagram from the DrugsPRO substance library.

Also known as: Restas, Kb-509, FZP

Classification

  • Chemical: Benzodiazepine
  • Psychoactive: Depressant
  • Tag: Anxiolytic
  • Tag: GABAergic
  • Tag: Habit-Forming
  • Tag: Muscle Relaxant
  • Tag: Sedative

Effects

  • Sedation
  • Muscle Relaxation
  • Physical Euphoria
  • Anxiolytic
  • Sedative
  • Dystaxia
  • Anxiety Suppression
  • Cognitive Euphoria
  • Motor Control Loss
  • Amnesia
  • Emotion Suppression
  • Delusions Of Sobriety
  • Disinhibition
  • Dulled Perception

Routes of Administration

Oral

Dosage

  • Threshold: 0.5 mg
  • Light: 0.5-1 mg
  • Common: 1-2.5 mg
  • Strong: 2.5-5 mg
  • Heavy: 5+ mg

Duration

  • Onset: 0.5-1.5 h
  • Comeup: 1-2 h
  • Peak: 2-12 h
  • Offset: 24-96 h
  • After Effects: 24-72 h
  • Total Duration: 60-90 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Flutoprazepam - DrugsPRO substansvejledning

Flutoprazepam: Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life)

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