Mexedrone is a research chemical with very little history of human use prior to 2015. It was marketed as a legal alternative to mephedrone but is reported to be approximately 10-20 times weaker in potency, requiring higher doses to achieve comparable effects. The substance has been associated with significant sedation rather than stimulation, distinguishing it from mephedrone. Legal status varies by jurisdiction; it is controlled in Sweden, Switzerland, Brazil, and the United Kingdom under blanket bans on cathinones or psychoactive substances. Users should employ accurate milligram scales and practice harm reduction.
Mexedrone molecular structure diagram from the DrugsPRO substance library.
Also known as: 4-mmeoc, 4-mmc-meo
Classification
Chemical: Cathinone
Psychoactive: Entactogen
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Empathogen
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Tentative
Effects
Physical Euphoria
Sedation
Increased Perspiration
Temperature Regulation Suppression
Teeth Grinding
Nystagmus
Euphoria
Thought Acceleration
Thought Connectivity
Anxiety
Cognitive Fatigue
Depression
Tactile Enhancement
Spontaneous Physical Sensations
Auditory Enhancement
Dehydration
Vibrating Vision
Color Enhancement
Routes of Administration
Oral
Dosage
Threshold: 50 mg
Light: 100-150 mg
Common: 150-250 mg
Strong: 200-300 mg
Heavy: 350 mg
Duration
Onset: 0.5-1 h
Peak: 2-3 h
Offset: 1-2 h
After Effects: 2-12 h
Insufflated
Dosage
Threshold: 40 mg
Light: 60-80 mg
Common: 80-100 mg
Strong: 120-200 mg
Heavy: 200 mg
Duration
Onset: 0.08-0.33 h
Peak: 1.5-2.5 h
Offset: 1-2 h
After Effects: 2-12 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
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Mexedrone - DrugsPRO substansvejledning
Mexedrone: Mexedrone is a research chemical with very little history of human use prior to 2015. It was marketed as a legal alternative to mephedrone but is reported to be approximately 10-20 times weaker in potency, requiring higher doses to achieve comparable effects. The substance has been associ
