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Morfin-N-oxid

Morphine-N-oxide (genomorphine) is an active opioid metabolite of morphine. Morphine itself, in trials with rats, is 11–22 times more potent than morphine-N-oxide subcutaneously and 39–89 times more potent intraperitoneally. However, pretreatment with amiphenazole or tacrine increases the potency of morphine-N-oxide in relation to morphine. A possible explanation is that morphine-N-oxide is rapidly inactivated in the liver and impairment of inactivation processes or enzymes increases functionality.

Classification

  • Chemical: Medicine
  • Chemical: Opioid
  • Psychoactive: Depressant

Effects

  • Sedation
  • Motor Impairment
  • Respiratory Depression
  • Constipation
  • Pupil Constriction
  • Itchiness
  • Reduced Anxiety
  • Euphoria
  • Anxiety Suppression
  • Dulled Perception

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Morphine-N-oxide - DrugsPRO substansvejledning

Morphine-N-oxide: Morphine-N-oxide (genomorphine) is an active opioid metabolite of morphine. Morphine itself, in trials with rats, is 11–22 times more potent than morphine-N-oxide subcutaneously and 39–89 times more potent intraperitoneally. However, pretreatment with amiphenazole or tacrine increa

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