Propylhexedrine is legally available as an over-the-counter nasal decongestant in the United States under the brand name Benzedrex. Recreational use typically involves extracting the drug-soaked cotton from inhalers, a practice that carries significant health risks that have not been extensively studied. Propylhexedrine produces more pronounced peripheral effects (vasoconstriction, cardiovascular strain) compared to amphetamines due to reduced blood-brain barrier permeability. Use extreme caution with dosing and avoid use if you have cardiovascular conditions or personal/family history of psychotic disorders. Always use harm reduction practices including accurate weighing, avoiding combinations with other stimulants, staying hydrated, and monitoring vital signs.
Propylhexedrin molecular structure diagram from the DrugsPRO substance library.
Also known as: Obesin, Benzedrex, Propylhexadrine, Hexahdromethamphetamine
Classification
Chemical: Amphetamine
Psychoactive: Stimulant
Tag: Common
Tag: Cycloalkylamine
Tag: Habit-Forming
Tag: Over-the-counter
Effects
Stimulation
Vasoconstriction
Increased Blood Pressure
Increased Heart Rate
Nausea
Abnormal Heartbeat
Focus Enhancement
Motivation Enhancement
Euphoria
Anxiety
Thought Acceleration
Wakefulness
Increased Libido
Appetite Suppression
Light Sensitivity
Routes of Administration
Oral
Dosage
Threshold: 10 mg
Light: 30-60 mg
Common: 60-120 mg
Strong: 120-180 mg
Heavy: 180 mg
Duration
Onset: 0.2-0.5 h
Comeup: 0.2-1.5 h
Peak: 2-5 h
Offset: 1-3 h
After Effects: 2-12 h
Insufflated
Dosage
Common: 30-75 mg
Light: 10-30 mg
Strong: 75-100 mg
Duration
No data available for this section yet.
Insufflated (Pure)
Dosage
Common: 15-30 mg
Light: 5-15 mg
Strong: 30-50 mg
Duration
No data available for this section yet.
Oral (Benzedrex)
Dosage
Common: 60-125 mg
Heavy: 250 mg
Light: 20-60 mg
Strong: 125-250 mg
Duration
No data available for this section yet.
Oral (Pure)
Dosage
Common: 20-50 mg
Light: 10-20 mg
Strong: 50 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Propylhexedrine - DrugsPRO substansvejledning
Propylhexedrine: Propylhexedrine is legally available as an over-the-counter nasal decongestant in the United States under the brand name Benzedrex. Recreational use typically involves extracting the drug-soaked cotton from inhalers, a practice that carries significant health risks that have not bee
