Library
5-Cl-AMT
5-Cl-AMT (5-chloro-α-methyltryptamine; PAL-542) combines three properties with harm-reduction implications: it is a serotonin-dopamine releasing agent, a potent 5-HT2A agonist, and an in vitro MAO-A inhibitor. Treat it as an MAOI during the session window even though clinical reversibility is not established. Start with a microtest of 0.5-1 mg to gauge sensitivity; community trials report activity at 1-2 mg and full days' worth of effects from 8-12 mg. Because the come-up is slow and the duration long, redosing is usually unnecessary and can produce a late, heavy body load. Volumetric dosing is strongly advised so that sub-1 mg adjustments are possible; weigh at least 10-20 mg on a 0.001 g scale, dissolve to make 1 mg/mL or 0.5 mg/mL, and measure with an oral syringe.
Also known as: Pal-542
Classification
- Chemical: Tryptamine
- Psychoactive: Entactogen
- Psychoactive: Psychedelic
- Psychoactive: Stimulant
- Tag: Research-Chemical
Effects
- Pupil Dilation
- Mild Tremor Or Jaw Tension
- Increased Bodily Temperature
- Nystagmus
- Increased Heart Rate
- Stimulation
- Entactogenic Warmth And Sociability
- Time Distortion
- Talkativeness
- Alertness Enhancement
- Euphoria
- Anxiety
- Color Enhancement
- Spontaneous Physical Sensations
- Light Sensitivity
- Visual Distortion
Routes of Administration
Oral
Dosage
- Threshold: 0.5-1 mg
- Light: 1-3 mg
- Common: 3-8 mg
- Strong: 8-12 mg
- Heavy: 12 mg
Duration
- Onset: 0.5-1.5 h
- Comeup: 1-2 h
- Peak: 4-8 h
- Offset: 4-8 h
- After Effects: 12-48 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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