Roughly 2-3× the potency of racemic ketamine with a markedly longer duration. Produces strong dissociation that can turn dysphoric or delusional at high doses. Urinary and bladder toxicity similar to or worse than ketamine has been reported with heavy use. Psychosis-like reactions, mania, and persisting cognitive deficits observed after chronic binges. Pure free-base easily aerosolizes and accidental inhalation can lead to rapid blackout.
DCK molecular structure diagram from the DrugsPRO substance library.
Also known as: Dxe, O-pcm, 2'-oxo-pcm, Deschloroketamine
Classification
Chemical: Arylcyclohexylamine
Psychoactive: Dissociative
Tag: Habit-Forming
Tag: Hallucinogen
Tag: Research-Chemical
Tag: Tentative
Effects
Analgesia
Body Lightness
Creativity Enhancement
Nausea
Physical Euphoria
Sedation
Anxiety Suppression
Cognitive Disconnection
Cognitive Euphoria
Compulsive Redosing
Conceptual Thinking
Consciousness Disconnection
Closedeye Visuals
Double Vision
Increased Music Appreciation
Spatial Disorientation
Tactile Suppression
Visual Disconnection
Routes of Administration
Oral
Dosage
Threshold: 10 mg
Light: 10-20 mg
Common: 20-30 mg
Strong: 30-50 mg
Heavy: 50 mg
Duration
Onset: 0.08-0.5 h
Comeup: 0.5-1 h
Peak: 1.5-2.5 h
Offset: 1-2 h
After Effects: 3-24 h
Insufflated
Dosage
Threshold: 5 mg
Light: 10-15 mg
Common: 15-25 mg
Strong: 25-40 mg
Heavy: 40 mg
Duration
Onset: 0.03-0.17 h
Comeup: 0.25-0.5 h
Peak: 1-1.5 h
Offset: 0.5-1 h
After Effects: 1-12 h
Smoked
Dosage
Threshold: 5 mg
Light: 5-10 mg
Common: 10-20 mg
Strong: 20-40 mg
Heavy: 40 mg
Duration
Onset: 0.02-0.03 h
Comeup: 0.08-0.25 h
Peak: 0.17-0.5 h
Offset: 0.25-0.5 h
After Effects: 1-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
Get the full DrugsPRO experience
Open the interactive DrugsPRO app for search, saved items, interactions, and deeper harm reduction tools.
Get the PRO test kit. The simple, quick and reliable drug checking test kit. Visit https://protestkit.eu
DCK - DrugsPRO Substanzleitfaden
DCK: Roughly 2-3× the potency of racemic ketamine with a markedly longer duration. Produces strong dissociation that can turn dysphoric or delusional at high doses. Urinary and bladder toxicity similar to or worse than ketamine has been reported with heavy use. Psychosis-like reactions, mania, and p
