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Dextropropoxyphen

Dextropropoxyphene (also known as Propoxyphene and Darvon) is a synthetic opioid of the phenylpropylamine chemical class. Like other substances in its class, particularly tapentadol and tramadol, it produces mild euphoric, analgesic, sedative and antitussive effects when administered (typically orally, but sometimes intravenous or rectally).[citation needed] Notably, it is reported to produce significantly less euphoria in comparison to other opioids.[citation needed].

Dextropropoxyphen molecular structure
Dextropropoxyphen molecular structure diagram from the DrugsPRO substance library.

Also known as: Darvon, Capadex, Darvocet, Di-gesic, Co-proxamol

Classification

  • Chemical: Opioid
  • Psychoactive: Depressant
  • Tag: Habit-Forming
  • Tag: Phenylpropylamine

Effects

  • Sedation
  • Motor Impairment
  • Respiratory Depression
  • Constipation
  • Pupil Constriction
  • Itchiness
  • Reduced Anxiety
  • Euphoria
  • Anxiety Suppression
  • Sadness
  • Cognitive Euphoria
  • Compulsive Redosing
  • Dulled Perception
  • Blurred Vision
  • Disinhibition
  • Auditory Hallucination
  • Internal Music
  • Sound Amplification

Routes of Administration

Oral

Dosage

  • Common: 65-100 mg
  • Light: 30-65 mg
  • Strong: 100-200 mg
  • Threshold: 15 mg
  • Heavy: 200 mg

Duration

  • Onset: 0.3-0.5 h
  • Peak: 1-4 h
  • After Effects: 1-6 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Dextropropoxyphene - DrugsPRO Substanzleitfaden

Dextropropoxyphene: Dextropropoxyphene (also known as Propoxyphene and Darvon) is a synthetic opioid of the phenylpropylamine chemical class. Like other substances in its class, particularly tapentadol and tramadol, it produces mild euphoric, analgesic, sedative and antitussive effects when administ

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