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Thebaine

Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects. At high doses, it causes convulsions similar to strychnine poisoning. The synthetic enantiomer (+)-thebaine does show analgesic effects apparently mediated through opioid receptors, unlike the inactive natural enantiomer (−)-thebaine. While thebaine is not used therapeutically, it is the main alkaloid extracted from Papaver bracteatum and can be converted industrially into a variety of compounds that do have medicinal value.

Thebaine molecular structure
Thebaine molecular structure diagram from the DrugsPRO substance library.

Also known as: Thebain

Classification

  • Chemical: Medicine
  • Chemical: Opioid
  • Psychoactive: Depressant

Effects

  • Sedation
  • Motor Impairment
  • Respiratory Depression
  • Constipation
  • Pupil Constriction
  • Itchiness
  • Reduced Anxiety
  • Euphoria
  • Anxiety Suppression
  • Dulled Perception

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Thebaine - DrugsPRO Substanzleitfaden

Thebaine: Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rat

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