Library
Tilmetamin
Tilmetamine (2-(methylamino)-2-(thiophen-2-yl)cyclohexan-1-one) is the N-methyl homolog of Til-ET-amine that reached grey-market vendors in 2024. Community reports place potency roughly five to seven times that of ketamine: 2-5 mg insufflated already produces dissociation, while 10-20 mg has left users with vertigo, tremor, depersonalisation, and dysphoria lasting days. The powder is hygroscopic and clings electrostatically, so volumetric dosing in PG or an ethanol-water mix (for example 10 mg/mL) is far safer than chasing individual milligram shards. Vendors advertise rapid onset (1-10 minutes IM/IN) and a 1-2 hour elimination half-life, yet many users describe a heavier body-load than ketamine with little euphoria and pronounced after-effects. Stacking doses easily leads to ataxia and next-day fatigue; start with micro-doses, avoid redosing, and assume full cross-tolerance with other arylcyclohexylamines.
Classification
- Chemical: Arylcyclohexylamine
- Psychoactive: Dissociative
- Tag: Hallucinogen
- Tag: Research-Chemical
Effects
- Analgesia
- Vertigo
- Muscle Tremors
- Pain Relief
- Incoordination
- Impaired Balance
- Dissociation
- Physical Autonomy
- Motor Control Loss
- Depersonalization
- Derealization
- Conceptual Thinking
- Visual Distortion
- Auditory Enhancement
- Spatial Disorientation
- Visual Snow
- Open Eye Visuals
- Auditory Warping
Routes of Administration
Insufflated
Dosage
- Threshold: 1–2 mg
- Light: 2–5 mg
- Common: 5–10 mg
- Strong: 10–20 mg
- Heavy: 20 mg+
Duration
- Onset: 0.08-0.25 h
- Comeup: 0.33-0.67 h
- Peak: 0.5-2 h
- Offset: 6-12 h
- After Effects: 12-336 h
- Total Duration: 8-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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