Extremely limited human data. All dosage and duration figures are extrapolated from user reports and close structural analogues (α-PHP, α-PVP, MDPV). Functions as a potent dopamine and norepinephrine transporter inhibitor; serotonin activity appears minimal. Acute risks include tachycardia, hypertension, vasoconstriction, hyperthermia, anxiety, paranoia, and rhabdomyolysis at high doses. Chronic use associated with insomnia, weight loss, compulsive use, psychosis, and cardiovascular strain.
Also known as: 3,4-dmohp, 3,4-dimethoxy-α-php
Classification
Chemical: Cathinone
Psychoactive: Stimulant
Tag: Habit-Forming
Tag: Pyrrolidine
Tag: Research-Chemical
Effects
Stimulation
Physical Euphoria
Bruxism
Vasoconstriction
Increased Heart Rate
Increased Blood Pressure
Cognitive Euphoria
Compulsive Redosing
Focus Enhancement
Motivation Enhancement
Increased Sociability
Anxiety
Increased Libido
Appetite Suppression
Light Sensitivity
Disinhibition
Dehydration
Tactile Enhancement
Routes of Administration
Oral
Dosage
Threshold: 5 mg
Light: 10 – 20 mg
Common: 20 – 40 mg
Strong: 40 – 60 mg
Heavy: 60 mg +
Duration
Onset: 0.25-0.75 h
Comeup: 0.5-1 h
Peak: 1-2.5 h
Offset: 1-2 h
After Effects: 6-24 h
Total Duration: 3-6 h
Insufflated
Dosage
Threshold: 2 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 50 mg
Heavy: 50 mg +
Duration
Onset: 0.08-0.17 h
Comeup: 0.17-0.33 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 6-24 h
Total Duration: 1.5-4 h
Smoked
Dosage
Threshold: 1 mg
Light: 3 – 10 mg
Common: 10 – 20 mg
Strong: 20 – 30 mg
Heavy: 30 mg +
Duration
Onset: 0-0.03 h
Comeup: 0.08-0.25 h
Peak: 0.25-1 h
Offset: 1-2 h
After Effects: 6-24 h
Total Duration: 1.5-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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DMO-PHP - Οδηγός ουσίας DrugsPRO
DMO-PHP: Extremely limited human data. All dosage and duration figures are extrapolated from user reports and close structural analogues (α-PHP, α-PVP, MDPV). Functions as a potent dopamine and norepinephrine transporter inhibitor; serotonin activity appears minimal. Acute risks include tachycardia,
