Morphine is the principal alkaloid of the opium poppy (Papaver somniferum) and the prototypical opioid analgesic. First isolated by Friedrich Sertürner in 1805, it has served as the foundation from which numerous semi-synthetic opioids have been derived. Morphine produces potent analgesia, euphoria, and sedation, and is used clinically for the management of moderate to severe pain. Its use carries significant risks of tolerance, physical dependence, and abuse.
Μορφίνη molecular structure diagram from the DrugsPRO substance library.
Also known as: M, Morpho, Monkey, Dreamer, Roxanol, Morphia, Morphium, MS Contin, MSIR, Kadian, Avinza, Oramorph SR / Oramorph, Duramorph, Infumorph, Arymo ER, Statex, Miss Emma, God’s Drug, Mister Blue, Morf, Unkie
Classification
Chemical: Medicine
Chemical: Morphinan
Chemical: Opioid
Psychoactive: Depressant
Tag: Alkaloid
Tag: Common
Tag: Habit-Forming
Effects
Pain Relief
Respiratory Depression
Itchiness
Cough Suppression
Difficulty Urinating
Nausea
Euphoria
Anxiety Suppression
Compulsive Redosing
Mood Lift
Cognitive Euphoria
Sadness
Decreased Libido
Internal Hallucination
Closed Eye Visuals
Lattice Imagery
Increased Music Appreciation
Visual Trails
Routes of Administration
Oral
Dosage
Heavy: 60+ mg
Light: 5-10 mg
Common: 10 – 20 mg
Strong: 20 – 30 mg
Threshold: < 10 mg
Bioavailability: 60 mg
Duration
Onset: 0.17-0.5 h
Comeup: 0.33-0.67 h
Peak: 2-3 h
Offset: 1-3 h
After Effects: 6-12 h
Total Duration: 4-6 h
Intravenous
Dosage
Heavy: 30+ mg
Light: 3.33 – 5 mg
Common: 5 – 7.5 mg
Strong: 7.5 – 10 mg
Threshold: 3.33 mg
Bioavailability: 100%
Duration
Onset: 0-0.01 h
Comeup: 0.03-0.08 h
Peak: 0.08-0.25 h
Offset: 1-1.5 h
After Effects: 4-12 h
Total Duration: 3-5 h
Intramuscular
Dosage
Heavy: 30+ mg
Light: 2-5 mg
Common: 5-15 mg
Strong: 15-30 mg
Threshold: 2 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Morphine - Οδηγός ουσίας DrugsPRO
Morphine: Morphine is the principal alkaloid of the opium poppy (Papaver somniferum) and the prototypical opioid analgesic. First isolated by Friedrich Sertürner in 1805, it has served as the foundation from which numerous semi-synthetic opioids have been derived. Morphine produces potent analgesia,
