Noopept (omberacetam, GVS-111) is a peptide-derived nootropic first synthesized in 1996 and developed as a prescription medication in Russia. It has become one of the most widely used cognitive enhancers, often taken in combination 'stacks' with other nootropics. Noopept is commonly attributed with temporarily enhancing concentration, focus, and memory recall. Daily use may lead to dependence, with withdrawal reportedly causing negative cognitive effects.
Noopept molecular structure diagram from the DrugsPRO substance library.
Also known as: Gvs-111, Sgs-111, Omberacetam, N-phenylacetyl-L-prolylglycine ethyl ester, DVD-111
Classification
Chemical: Racetam
Psychoactive: Nootropic
Tag: Peptide
Tag: Peptide derivative
Tag: Research-Chemical
Effects
Spontaneous Tactile Sensations
Stimulation
Insomnia
Physical Energy
Difficulty Falling Asleep
Headache
Wakefulness
Thought Connectivity
Focus Enhancement
Thought Acceleration
Motivation Enhancement
Memory Enhancement
Acuity Enhancement
Color Enhancement
Increased Music Appreciation
Light Sensitivity
Visual Acuity Enhancement
Open Eye Visuals
Routes of Administration
Insufflated
Dosage
Light: 2 – 5 mg
Common: 5 – 10 mg
Strong: 10-20 mg
Threshold: 2 mg
Heavy: 20 mg
Duration
Onset: 0-0.1 h
Peak: 2 h
Offset: 3 h
Oral
Dosage
Heavy: 40+ mg
Light: 5-10 mg
Common: 10-20 mg
Strong: 10 – 20 mg
Threshold: 3–5 mg
Duration
After Effects: 0-12 h
Onset: 0.25-0.5 h
Peak: 0.75-2 h
Offset: 2-3 h
Total Duration: 3-6 h
Sublingual
Dosage
Light: 2 – 5 mg
Common: 5 – 10 mg
Strong: 12–20 mg
Threshold: 2–3 mg
Heavy: 20+ mg
Duration
Onset: 0.083-0.167 h
Peak: 0.5-1.5 h
Offset: 1.5-3 h
After Effects: 0-12 h
Total Duration: 3-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
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Noopept - Οδηγός ουσίας DrugsPRO
Noopept: Noopept (omberacetam, GVS-111) is a peptide-derived nootropic first synthesized in 1996 and developed as a prescription medication in Russia. It has become one of the most widely used cognitive enhancers, often taken in combination 'stacks' with other nootropics. Noopept is commonly attribu
