Library
2C-TFM
2C-TFM is the most potent simple 2C analogue, with human active doses of 3-6 mg according to Trachsel and Shulgin. It rivals DOI and DOB in receptor binding affinity (Ki ≈ 75 nM at 5-HT2A/C). Because it is usually synthesized from 2C-I, retail batches from the mid-2000s were often contaminated with ~50% unreacted 2C-I, leading to mixed effects and legal complications in jurisdictions where 2C-I is prohibited. Purity must be confirmed with multi-reagent testing plus quantitative chromatography whenever possible. The compound produces an unusually clear-headed, color-saturated visual field with mild bodily stimulation and minimal vasoconstriction at doses ≤5 mg.
Also known as: 2c-cf3
Classification
- Chemical: Phenethylamine
- Psychoactive: Psychedelic
- Tag: 2C-X
- Tag: Research-Chemical
Effects
- Stimulation
- Pupil Dilation
- Nausea
- Dilated Pupils
- Insomnia
- Restlessness
- Euphoria
- Analysis Enhancement
- Thought Organization
- Introspection
- Time Distortion
- Confusion
- Color Enhancement
- Music Enhancement
- Synaesthesia
- Visual Distortion
- Tracers
- Pattern Recognition Enhancement
Routes of Administration
Oral / Sublingual
Dosage
- Threshold: 1 mg
- Light: 1-2 mg
- Common: 2-5 mg
- Strong: 5-8 mg
- Heavy: 8 mg
Duration
- Onset: 0.25-0.5 h
- Comeup: 0.5-1 h
- Peak: 1-3 h
- Offset: 2-3 h
- After Effects: 2-6 h
Insufflated (Intranasal)
Dosage
- Threshold: 500 ug
- Light: 500-1500 ug
- Common: 1.5-4 mg
- Strong: 1500 mg
- Heavy: 1500 mg
Duration
- Onset: 0.08-0.25 h
- Comeup: 0.25-0.5 h
- Peak: 1-3 h
- Offset: 2-3 h
- After Effects: 2-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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