Library
2-MeO-DMT
2-MeO-DMT (2-methoxy-N,N-dimethyltryptamine) is a rare research chemical first described in the 1960s. Human data are sparse; doses and timelines above are extrapolated from a handful of forum reports (DMT-Nexus, Reddit) and its lower affinity for 5-HT2A relative to DMT in vitro. Users consistently describe markedly milder visuals than DMT but pronounced bodily warmth, slight dissociation, and a dreamy head-space. Many compare it to a cross between low-dose DMT and 5-MeO-DMT, though without the ego-dissolving intensity. Because safety data are limited, start with allergy test (<3 mg vaporized) and titrate slowly.
Classification
- Chemical: Tryptamine
- Psychoactive: Psychedelic
- Tag: Hallucinogen
- Tag: Research-Chemical
Effects
- Warm Body Glow
- Physical Heaviness Or Lethargy
- Nausea At Higher Doses
- Anxiolysis
- Head Pressure Or Sinus Discomfort
- Stimulation
- Dreamlike Mental State
- Time Dilation
- Slight Dissociation
- Mild Euphoria
- Introspection
- Euphoria
- Mild Closedeye Visuals
- Audio Enhancement
- Visual Distortion
- Color Enhancement
Routes of Administration
Vaporized
Dosage
- Threshold: 5–10 mg
- Light: 10–30 mg
- Common: 30–60 mg
- Strong: 60–90 mg
- Heavy: 90 mg
Duration
- Onset: 0-0.01 h
- Peak: 0.08-0.25 h
- Offset: 0.17-0.33 h
- After Effects: 0.5-2 h
Insufflated
Dosage
- Threshold: 10 mg
- Light: 20–40 mg
- Common: 40–70 mg
- Strong: 70–100 mg
- Heavy: 100 mg
Duration
- Onset: 0.08-0.25 h
- Peak: 0.33-0.75 h
- Offset: 0.67-1 h
- After Effects: 0.5-2 h
Oral
Dosage
- Threshold: 30 mg
- Light: 40–70 mg
- Common: 70–120 mg
- Strong: 120–180 mg
- Heavy: 180 mg
Duration
- Onset: 0.5-1 h
- Peak: 1-2 h
- Offset: 1-2 h
- After Effects: 0.5-2 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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