Library
2-Me-PiHP
2-Me-PiHP is a 2-methyl analog of α-PiHP featuring potent dopamine and norepinephrine transporter inhibition with markedly shortened duration compared to the parent compound, increasing compulsive redosing liability. Vaporized route produces intense crack cocaine-like rush lasting under 30 minutes, driving rapid pipe reloading. Crystalline HCl salt vaporizes around 210°C but generates caustic aerosol causing lung discomfort and transient dyspnea; propylene glycol/glycerin e-liquid (60:40) mitigates irritation but encourages covert dosing. Insufflation of 40+ mg causes severe burn and vasoconstriction; isotonic saline lavage plus vitamin E oil post-use reduces mucosal injury. Oral dosing extends effects to approximately 4 hours but increases risk of tachycardia (HR >120 bpm) and marked vasospasm.
Also known as: 2-me-alfa-pihp, 2-methyl-alpha-pihp
Classification
- Chemical: Cathinone
- Psychoactive: Stimulant
- Tag: Habit-Forming
- Tag: Pyrrolidine
- Tag: Research-Chemical
Effects
- Stimulation
- Physical Euphoria
- Teeth Grinding
- Vasoconstriction
- Increased Heart Rate
- Temperature Regulation Suppression
- Euphoria
- Cognitive Euphoria
- Compulsive Redosing
- Motivation Enhancement
- Focus Enhancement
- Thought Acceleration
- Increased Libido
- Appetite Suppression
- Dehydration
- Light Sensitivity
- Disinhibition
- Tactile Enhancement
Routes of Administration
Insufflated
Dosage
- Threshold: 5-10 mg
- Light: 10-20 mg
- Common: 20-40 mg
- Strong: 40-70 mg
- Heavy: 70 mg
Duration
- Onset: 0.08-0.17 h
- Comeup: 0.17-0.33 h
- Peak: 0.5-1.5 h
- Offset: 1-3 h
- After Effects: 4-10 h
Oral
Dosage
- Threshold: 10 mg
- Light: 15-30 mg
- Common: 30-60 mg
- Strong: 60-90 mg
- Heavy: 90 mg
Duration
- Onset: 0.33-0.67 h
- Comeup: 0.5-1 h
- Peak: 1-3 h
- Offset: 2-3 h
- After Effects: 4-10 h
Vaporized / Smoked
Dosage
- Threshold: 3-5 mg
- Light: 5-12 mg
- Common: 12-20 mg
- Strong: 20-35 mg
- Heavy: 35 mg
Duration
- Onset: 0.01 h
- Comeup: 0.02-0.08 h
- Peak: 0.33-0.75 h
- Offset: 0.5-1.5 h
- After Effects: 4-10 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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