Library
3-Me-PCPy
3-Me-PCPy is an arylcyclohexylamine derivative with an uncommon dual pharmacological profile, producing both dissociative and stimulant effects. Unlike most substances in its class, it combines potent NMDA antagonism with triple monoamine reuptake inhibition affecting serotonin, dopamine, and noradrenaline. It also displays high affinity for sigma receptors. This broad spectrum of activity distinguishes it from related arylcyclohexylamines, contributing to its unusual combination of stimulant and dissociative properties.
Also known as: M3ppy, Tolicyclidine, 3-methyl-PCPy
Classification
- Chemical: Arylcyclohexylamine
- Psychoactive: Dissociative
- Psychoactive: Stimulant
Effects
- Stimulation
- Abnormal Heartbeat
- Increased Blood Pressure
- Increased Heart Rate
- Increased Perspiration
- Tactile Disconnection
- Anxiety Suppression
- Euphoria
- Mania
- Immersion Enhancement
- Dissociation
- Dizziness
- Disinhibition
- Increased Music Appreciation
- Spontaneous Physical Sensations
- Appetite Suppression
- Auditory Hallucination
- Auditory Distortion
Routes of Administration
Oral
Dosage
- Heavy: 50+ mg
- Light: 10 mg
- Common: 8 – 16 mg
- Strong: 16 – 25 mg
- Threshold: 7-10 mg
Duration
- Onset: 0.33-0.67 h
- Comeup: 0.5-2 h
- Peak: 0.5-1.5 h
- Offset: 1.5-3 h
- After Effects: 6-24 h
- Total Duration: 2.5-4 h
Insufflated
Dosage
- Heavy: 35+ mg
- Light: 3 – 6 mg
- Common: 6 – 12 mg
- Strong: 12 – 20 mg
- Threshold: 3 mg
Duration
- Onset: 0.03-0.08 h
- Comeup: 0.5-1.5 h
- Peak: 0.33-1 h
- Offset: 0.5-1 h
- After Effects: 4-24 h
- Total Duration: 2-4 h
Rectal
Dosage
- Heavy: 35+ mg
- Light: 5-10 mg
- Common: 10-20 mg
- Strong: 20-35 mg
- Threshold: 5 mg
Duration
- Onset: 0.08-0.17 h
- Peak: 0.5-1.25 h
- Offset: 1-2 h
- After Effects: 2-8 h
- Total Duration: 2.5-4 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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