Library
4-AcO-DET
4-AcO-DET is a synthetic psychedelic of the tryptamine class, first synthesized by Albert Hofmann at the Sandoz laboratory in 1958. It is chemically related to psilocin and belongs to a series of substituted tryptamines that includes 4-AcO-MET and 4-AcO-DMT. Its effects are generally compared to those of psilocybin mushrooms. It remains a lesser-known research chemical, typically encountered as a slightly off-white powder and most commonly administered orally.
Also known as: Ethacetin, Ethylacybin, 4-acetoxy-det, O-acetyl-4-HO-DET
Classification
- Chemical: Tryptamine
- Psychoactive: Psychedelic
- Tag: Research-Chemical
- Tag: substituted tryptamine
- Tag: Tentative
Effects
- Spontaneous Tactile Sensations
- Increased Heart Rate
- Nausea
- Pupil Dilation
- Headache
- Difficulty Urinating
- Analysis Enhancement
- Conceptual Thinking
- Delusion
- Emotion Enhancement
- Immersion Enhancement
- Memory Suppression
- Bodily Control Enhancement
- Tactile Enhancement
- Hallucinations
- Drifting
- Color Shifting
- Symmetrical Texture Repetition
Routes of Administration
Oral
Dosage
- Heavy: 40+ mg
- Light: 5 – 15 mg
- Common: 15 – 20 mg
- Strong: 20 – 35 mg
- Threshold: 2 – 5 mg
Duration
- Onset: 0.33-1 h
- Comeup: 1-1.5 h
- Peak: 1.5-3 h
- Offset: 1-2 h
- After Effects: 7-24 h
- Total Duration: 3-8 h
Smoked
Dosage
No data available for this section yet.
Duration
- Peak: 0.08-0.5 h
- Onset: 0.02-0.08 h
- Offset: 0.5-1.5 h
- After Effects: 1-6 h
- Total Duration: 0.5-1.5 h
Insufflated
Dosage
- Heavy: 28+ mg
- Light: 4-8 mg
- Common: 8-18 mg
- Strong: 18-28 mg
- Threshold: 2-4 mg
Duration
- Onset: 0.08-0.33 h
- Peak: 0.5-1.5 h
- Offset: 1.5-3 h
- After Effects: 3-12 h
- Total Duration: 1.5-3.5 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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