Diclazepam is a benzodiazepine and functional analog of diazepam (Valium). Leo Sternbach and colleagues at Hoffman-La Roche first synthesized it in 1960, but it is not approved for medical use and is instead sold as a research chemical. In animal models, diclazepam exhibits long-acting anxiolytic, sedative, hypnotic, anticonvulsant, muscle relaxant, and amnestic properties comparable to diazepam. Its efficacy and safety have not been evaluated in humans.
Diclazepam molecular structure diagram from the DrugsPRO substance library.
Also known as: Chlorodiazepam, 2'-chloro-diazepam, Ro5-3448
Classification
Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anticonvulsant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Muscle Relaxant
Tag: Sedative
Effects
Sedation
Respiratory Depression
Muscle Relaxation
Anxiolytic
Sedative
Dystaxia
Amnesia
Anxiety Suppression
Thought Deceleration
Information Processing Suppression
Euphoria
Compulsive Redosing
Disinhibition
Delirious Hallucination
Dulled Perception
Open Eye Visuals
Double Vision
Blurred Vision
Routes of Administration
Oral
Dosage
Heavy: 4+ mg
Light: 0.5 – 1 mg
Common: 1 – 2 mg
Strong: 2 – 4 mg
Threshold: 0.5 mg
Duration
Onset: 0.25-1.5 h
After Effects: 24-72 h
Peak: 2-6 h
Offset: 6-24 h
Total Duration: 12-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
Get the full DrugsPRO experience
Open the interactive DrugsPRO app for search, saved items, interactions, and deeper harm reduction tools.
Get the PRO test kit. The simple, quick and reliable drug checking test kit. Visit https://protestkit.eu
Diclazepam - DrugsPRO substance guide
Diclazepam: Diclazepam is a benzodiazepine and functional analog of diazepam (Valium). Leo Sternbach and colleagues at Hoffman-La Roche first synthesized it in 1960, but it is not approved for medical use and is instead sold as a research chemical. In animal models, diclazepam exhibits long-acting a