MDDMA, or MDDM, also known as 3,4-methylenedioxy-N,N-dimethylamphetamine or as N,N-dimethyl-MDA or N-methyl-MDMA, is a psychoactive drug of the phenethylamine, amphetamine, and MDxx families. It is the N,N-dimethyl analogue of MDA and the N-methyl derivative of MDMA. The drug is a known synthetic impurity of MDMA and has also been described as a possible novel designer drug in 2025. In addition, (R)-MDDMA was characterized as a non-hallucinogenic psychoplastogen with antidepressant-like effects and improved safety relative to MDMA in 2026.
MDDM molecular structure diagram from the DrugsPRO substance library.
Also known as: 3,4-methylenedioxy-N,N- dimethylamphetamine
Classification
Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Psychedelic
Psychoactive: Stimulant
Effects
Increased Heart Rate
Stimulation
Insomnia
Pupil Dilation
Jaw Tension
Talkativeness
Alertness Enhancement
Euphoria
Anxiety
Wakefulness
Confusion
Light Sensitivity
Color Enhancement
Open Eye Visuals
Tactile Enhancement
Appetite Suppression
Routes of Administration
No route information available yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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MDDM - DrugsPRO substance guide
MDDM: MDDMA, or MDDM, also known as 3,4-methylenedioxy-N,N-dimethylamphetamine or as N,N-dimethyl-MDA or N-methyl-MDMA, is a psychoactive drug of the phenethylamine, amphetamine, and MDxx families. It is the N,N-dimethyl analogue of MDA and the N-methyl derivative of MDMA. The drug is a known synthe
