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MEAI

MEAI, also known as 5-methoxy-2-aminoindane (5-MeO-AI) and by its developmental code name CMND-100, is an entactogen-like psychoactive drug of the 2-aminoindane family. It is a cyclized phenethylamine and is the 2-aminoindane analogue of 3-methoxyamphetamine. The drug acts as a serotonin–norepinephrine releasing agent (SNRA) or as a modestly selective serotonin releasing agent (SSRA), with about 6-fold preference for induction of serotonin over norepinephrine release. MEAI has been encountered as a novel designer recreational drug. It is also under development for potential medical use in the treatment of alcoholism, cocaine use disorder, metabolic syndrome, and obesity.

MEAI molecular structure
MEAI molecular structure diagram from the DrugsPRO substance library.

Also known as: 5-methoxy-2-aminoindane, 5-MeO-AI, CMND-100, 5-Methoxy-2-indanamine

Classification

  • Chemical: Aminoindane
  • Chemical: Phenethylamine
  • Psychoactive: Entactogen
  • Psychoactive: Stimulant

Effects

  • Increased Heart Rate
  • Stimulation
  • Insomnia
  • Jaw Tension
  • Teeth Grinding
  • Pain Relief
  • Talkativeness
  • Alertness Enhancement
  • Euphoria
  • Anxiety
  • Wakefulness
  • Irritability
  • Light Sensitivity
  • Appetite Suppression
  • Increased Libido
  • Dehydration
  • Open Eye Visuals
  • Increased Music Appreciation

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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MEAI - DrugsPRO substance guide

MEAI: MEAI, also known as 5-methoxy-2-aminoindane (5-MeO-AI) and by its developmental code name CMND-100, is an entactogen-like psychoactive drug of the 2-aminoindane family. It is a cyclized phenethylamine and is the 2-aminoindane analogue of 3-methoxyamphetamine. The drug acts as a serotonin–norep

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