Psilocin

Psilocin is the pharmacologically active form of psilocybin and is rarely encountered as a pure synthetic compound. It is relatively unstable and readily forms blue degradation products when exposed to oxygen. Store in cool, dry, dark conditions. Unlike psilocybin mushrooms, pure psilocin has reduced nausea when taken on an empty stomach. Set and setting are critical to the experience.

Also known as: 4-ho-dmt, 4-oh-dmt, Psilocine, Psilotsin

Classification

Chemical: Tryptamine
Psychoactive: Entactogen
Psychoactive: Psychedelic
Tag: Empathogen
Tag: Hallucinogen
Tag: Plant-based
Tag: Research-Chemical
Tag: Serotonergic
Tag: substituted tryptamine
Tag: Tentative

Effects

Sedation
Physical Euphoria
Excessive Yawning
Nausea
Dilated Pupils
Temperature Regulation Suppression
Emotionality Enhancement
Empathy Enhancement
Cognitive Euphoria
Analysis Enhancement
Conceptual Thinking
Thought Connectivity
Perception Of Bodily Heaviness
Spontaneous Physical Sensations
Changes In Felt Bodily Form
Tactile Enhancement
Color Enhancement
Visual Acuity Enhancement

Routes of Administration

Oral

Dosage

Threshold: 5 mg
Light: 10-15 mg
Common: 15-25 mg
Strong: 25-40 mg
Heavy: 40 mg

Duration

Onset: 0.3-0.8 h
Comeup: 1.5-3 h
Peak: 2-3 h
Offset: 1.5-2 h
After Effects: 4-24 h

Insufflated

Dosage

Common: 5-10 mg
Light: 2.5-5 mg
Strong: 10-15 mg

Duration

No data available for this section yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

This static page is intended as a readable non-JS and prerender-friendly library export.

Get the full DrugsPRO experience

Open the interactive DrugsPRO app for search, saved items, interactions, and deeper harm reduction tools.

Get the PRO test kit. The simple, quick and reliable drug checking test kit. Visit https://protestkit.eu