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1-(2,5-Dimetoxibencil) piperazina

Very little peer-reviewed human data exist. Limited forensic reports indicate occasional appearance in illicit 'party pill' blends between 2013-2019. Animal receptor-binding screens show micromolar affinity for 5-HT2A/2C and moderate inhibition of serotonin uptake, suggesting a hybrid psychedelic-stimulant profile comparable to 4-bromo-2,5-dimethoxy-BZP (2C-B-BZP) but with lower potency. Users report a slow come-up, mild closed-eye visuals, warmth/euphoria, tachycardia, jaw tension and long-lasting stimulation. Nausea, vasoconstriction and headaches are common at >80 mg.

Also known as: 2c-benzylpiperazine, 2,5-dimethoxybenzyl, DMBZP

Classification

  • Chemical: Piperazine
  • Psychoactive: Psychedelic
  • Psychoactive: Stimulant
  • Tag: Benzylpiperazine
  • Tag: Hallucinogen
  • Tag: Research-Chemical

Effects

  • Stimulation
  • Teeth Grinding
  • Pupil Dilation
  • Nausea
  • Vasoconstriction
  • Restlessness
  • Euphoria
  • Increased Sociability
  • Anxiety
  • Wakefulness
  • Sociability Enhancement
  • Talkativeness
  • Visual Enhancement
  • Pattern Recognition Enhancement
  • Color Enhancement
  • Tactile Enhancement
  • Bodily Control Enhancement
  • Open Eye Visuals

Routes of Administration

Oral

Dosage

  • Threshold: 10 mg
  • Light: 20 – 40 mg
  • Common: 40 – 80 mg
  • Strong: 80 – 120 mg
  • Heavy: 120 mg +‎

Duration

  • Onset: 0.75-2 h
  • Comeup: 0.5-1.5 h
  • Peak: 3-6 h
  • Offset: 1.5-3 h
  • After Effects: 12-24 h
  • Total Duration: 6-10 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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1-(2,5-Dimethoxybenzyl) piperazine - Guía de sustancias de DrugsPRO

1-(2,5-Dimethoxybenzyl) piperazine: Very little peer-reviewed human data exist. Limited forensic reports indicate occasional appearance in illicit 'party pill' blends between 2013-2019. Animal receptor-binding screens show micromolar affinity for 5-HT2A/2C and moderate inhibition of serotonin uptake

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