3C-E

3,5-Dimethoxy-4-ethoxyamphetamine (commonly known as 3C-E or 3C-Escaline) is a synthetic psychedelic compound of the amphetamine chemical class. Although it's name suggests it may be related to the 2C-x family, this is not the case. 3C-E has the structure of escaline, a mescaline analogue, with an additional carbon rendering it a substituted amphetamine.

Also known as: 3c-escaline, Alpha‑methyl escaline

Classification

Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Research-Chemical
Tag: Substituted amphetamine

Effects

Mentalphysical Stimulation
Decreased Appetite
Pupil Dilation
Restlessness
Sweatingchills
Muscle Tension
Euphoria
Empathy
Insight
Change In Perception
Ego Softening
Confusion
Brightened Color
Closedopen Eye Visuals
Enhanced Tactile Sensation
Auditory Hallucination
Auditory Distortion
Pattern Recognition Enhancement

Routes of Administration

Oral

Dosage

Common: 35-50 mg
Light: 25-35 mg
Strong: 50-70 mg
Threshold: 15-25 mg
Heavy: >70 mg

Duration

Onset: 0.5-1.5 h
Peak: 4-8 h
Offset: 3-6 h
After Effects: 2-16 h
Total Duration: 8-14 h

Insufflated

Dosage

Threshold: 5–8 mg
Heavy: 70 mg
Common: 35-60 mg
Light: 20-35 mg
Strong: 60-70 mg

Duration

Onset: 0.05-0.3 h
Peak: 4-7 h
Offset: 2-5 h
After Effects: 2-12 h
Total Duration: 6-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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