Acetylfentanyl is a synthetic opioid of the anilidopiperidine class and a structural analog of fentanyl. Originally described in the 1960s alongside fentanyl itself, it has never been approved for medical use and has only appeared on the illicit market as a designer drug. It is estimated to be several times more potent than heroin yet roughly fifteen times less potent than fentanyl, still presenting significant overdose risk.
Acetilfentanilo molecular structure diagram from the DrugsPRO substance library.
Also known as: A-f, Desmethyl fentanyl, Desmethyl fentanyl, wrongly called china white
Classification
Chemical: Anilidopiperidine
Chemical: Opioid
Psychoactive: Depressant
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Synthetic opioid
Effects
Pupil Constriction
Difficulty Urinating
Respiratory Depression
Sedation
Pain Relief
Muscle Relaxation
Euphoria
Anxiety
Confusion
Focus Suppression
Dizziness
Mood Lift
Double Vision
Dehydration
Appetite Suppression
Decreased Libido
Orgasm Depression
Dulled Perception
Routes of Administration
Oral
Dosage
Heavy: 7 mg
Light: 1 – 3 mg
Common: 3 – 5 mg
Strong: 5 – 7 mg
Threshold: 1 mg
Duration
Onset: 0.08-0.33 h
After Effects: 1-8 h
Sublingual
Dosage
Heavy: 20 mg
Light: 2 – 10 mg
Common: 10 – 15 mg
Strong: 15 – 20 mg
Threshold: 2 mg
Duration
Onset: 0.33-0.67 h
Insufflated
Dosage
Heavy: 20 mg
Light: 2 – 10 mg
Common: 10 – 15 mg
Strong: 15 – 20 mg
Threshold: 2 mg
Duration
Onset: 0.1-0.2 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
This static page is intended as a readable non-JS and prerender-friendly library export.
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Acetylfentanyl - Guía de sustancias de DrugsPRO
Acetylfentanyl: Acetylfentanyl is a synthetic opioid of the anilidopiperidine class and a structural analog of fentanyl. Originally described in the 1960s alongside fentanyl itself, it has never been approved for medical use and has only appeared on the illicit market as a designer drug. It is estim
