A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.
Doxilamina molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Medicine
Psychoactive: Deliriant
Psychoactive: Depressant
Tag: Pharmaceutical
Effects
Sedation
Motor Impairment
Nausea
Dry Mouth
Pupil Dilation
Increased Heart Rate
Reduced Anxiety
Confusion
Motor Control Loss
Paranoia
Irritability
Psychosis
Dulled Perception
Auditory Hallucination
Cognitive Dysphoria
Perception Of Bodily Heaviness
Auditory Distortion
Visual Distortions
Routes of Administration
Oral
Dosage
Common: 200-350 mg
Heavy: 350 mg
Light: 75-200 mg
Threshold: 10 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Doxylamine - Guía de sustancias de DrugsPRO
Doxylamine: A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.