MDMPEA is an obscure research compound patented by Merck in 1956 as an antitussive but never marketed clinically. Animal studies showed only moderate cough-suppression efficacy. It is classified as Schedule I in the USA as a positional isomer of MDA, prohibiting all non-research human use. No verified human trials or reliable recreational reports exist in the literature. The compound undergoes rapid MAO-B metabolism, requiring extremely large doses to achieve CNS effects without enzyme inhibition.
MDMPEA molecular structure diagram from the DrugsPRO substance library.
Also known as: Mk-71, Homarylamine, N-methylhomopiperonylamine, N-methyl-PEA, N-methyl-beta-phenethylamine
Classification
Chemical: Phenethylamine
Psychoactive: Entactogen
Psychoactive: Stimulant
Tag: Research-Chemical
Effects
Stimulation
Increased Heart Rate
Physical Euphoria
Jaw Tension
Coldness
Tremor
Euphoria
Increased Focus
Anxiety
Time Distortion
Motivation Enhancement
Mental Clarity
Open Eye Visuals
Light Sensitivity
Appetite Suppression
Increased Libido
Dehydration
Routes of Administration
Oral
Dosage
Threshold: 100 mg
Light: 100-300 mg
Common: 300-600 mg
Strong: 600-900 mg
Heavy: 900 mg
Duration
Onset: 0.17-0.75 h
Comeup: 0.17-0.33 h
Peak: 0.33-0.67 h
Offset: 0.5-1.5 h
After Effects: 1-4 h
Total Duration: 0.25-1.5 h
Insufflated
Dosage
Threshold: 50 mg
Light: 50-150 mg
Common: 150-350 mg
Strong: 350-550 mg
Heavy: 550 mg
Duration
Onset: 0.05-0.17 h
Comeup: 0.08-0.25 h
Peak: 0.33-0.67 h
Offset: 0.5-1 h
After Effects: 0.75-3 h
Total Duration: 0.25-1 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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MDMPEA - Guía de sustancias de DrugsPRO
MDMPEA: MDMPEA is an obscure research compound patented by Merck in 1956 as an antitussive but never marketed clinically. Animal studies showed only moderate cough-suppression efficacy. It is classified as Schedule I in the USA as a positional isomer of MDA, prohibiting all non-research human use. N
