CBDVA is the carboxylic-acid precursor of cannabidivarin (CBDV); heating or vaping will largely decarboxylate it into CBDV. Pre-clinical data suggest anticonvulsant, anti-inflammatory, and 5-HT1A-mediated anti-nausea properties similar to CBDA, but human data are sparse. Like CBD, CBDVA appears to inhibit CYP3A4, CYP2C19 and CYP2C9, so therapeutic drug monitoring is advised when combined with narrow-therapeutic-index medications (e.g., warfarin, clobazam, tacrolimus). Because it is non-intoxicating, subjective effects are subtle; many users report clearer focus and reduced anxiety rather than overt euphoria. Long-term safety data are lacking; start low, especially if you have liver disease or take hepatically-metabolized drugs.
CBDVA molecular structure diagram from the DrugsPRO substance library.
Also known as: Cannabidivarinic acid
Classification
Chemical: Cannabinoid
Chemical: Medicine
Tag: Not psychoactive
Tag: Research-Chemical
Tag: Supplement
Effects
Anxiolysis
Reduced Inflammation Perception
Anticonvulsant Effects
Mild Stimulation At Low Doses
Sedation At Higher Doses
Antiemetic Effects
Subtle Relaxation
Mild Mood Elevation
Increased Focus
Routes of Administration
Oral
Dosage
Threshold: 5 mg
Light: 10-40 mg
Common: 40-100 mg
Strong: 100-200 mg
Heavy: 200 mg
Duration
Onset: 0.5-1.5 h
Comeup: 0.5-1 h
Peak: 2-4 h
Offset: 2-4 h
After Effects: 12 h
Sublingual
Dosage
Threshold: 3 mg
Light: 5-25 mg
Common: 25-80 mg
Strong: 80-150 mg
Heavy: 150 mg
Duration
Onset: 0.25-0.75 h
Comeup: 0.33-0.67 h
Peak: 1.5-3 h
Offset: 1.5-3 h
After Effects: 8 h
Vaporized
Dosage
Threshold: 2 mg
Light: 5-15 mg
Common: 15-40 mg
Strong: 40-80 mg
Heavy: 80 mg
Duration
Onset: 0.02-0.08 h
Comeup: 0.08-0.25 h
Peak: 0.17-0.5 h
Offset: 1-2 h
After Effects: 6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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CBDVA - DrugsPRO ainejuhend
CBDVA: CBDVA is the carboxylic-acid precursor of cannabidivarin (CBDV); heating or vaping will largely decarboxylate it into CBDV. Pre-clinical data suggest anticonvulsant, anti-inflammatory, and 5-HT1A-mediated anti-nausea properties similar to CBDA, but human data are sparse. Like CBD, CBDVA appea
