Medasepaam

Medazepam is a long-acting benzodiazepine prodrug that metabolizes to diazepam and nordazepam, producing prolonged anxiolytic and sedative effects. Due to its very long half-life (36-200 hours) and active metabolites, the drug accumulates with repeated dosing, increasing risks of sedation and cognitive impairment. Withdrawal can be severe after prolonged use and requires medical supervision with gradual dose reduction. Elderly patients and those with hepatic impairment should use reduced doses.

Also known as: Talis, Resmit, Narsis, Nobrium, Rudotel, Ansilan, Rusedal, Lerisum, Medacepan, Megasedan, Debrum, Tranquirax, Nobritol

Classification

Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Muscle Relaxant

Effects

Sedation
Muscle Relaxation
Physical Euphoria
Respiratory Depression
Incoordination
Impaired Balance
Anxiety Suppression
Motor Control Loss
Memory Suppression
Thought Deceleration
Emotion Suppression
Cognitive Euphoria
Disinhibition
Dulled Perception

Routes of Administration

Oral

Dosage

Threshold: 2.5 mg
Light: 5-10 mg
Common: 10-30 mg
Strong: 20-40 mg
Heavy: 60+ mg

Duration

Onset: 0.5-1 h
Comeup: 0.5-1.5 h
Peak: 1-2 h
Offset: 6-12 h
After Effects: 12-72 h
Total Duration: 6-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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