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Metisolaam

Metizolam is a synthetic depressant of the thienotriazolodiazepine class and the demethylated analogue of etizolam. A Japanese company patented it in 1995 as a possible anxiolytic, but it saw little to no human use before appearing as a grey-area research chemical in September 2015. Compared to etizolam, it is reportedly half as potent with a 60% longer half-life, producing similar anxiolytic, sedative, and muscle relaxant effects.

Metisolaam molecular structure
Metisolaam molecular structure diagram from the DrugsPRO substance library.

Also known as: Metiz, Desmethyletizolam

Classification

  • Chemical: Benzodiazepine
  • Psychoactive: Depressant
  • Tag: Anxiolytic
  • Tag: GABAergic
  • Tag: Habit-Forming
  • Tag: Muscle Relaxant
  • Tag: Research-Chemical
  • Tag: Tentative
  • Tag: Thienodiazepine
  • Tag: Thienotriazolodiazepine

Effects

  • Sedation
  • Respiratory Depression
  • Muscle Relaxation
  • Motor Impairment
  • Anxiolytic
  • Sedative
  • Anxiety Suppression
  • Thought Deceleration
  • Analysis Suppression
  • Information Processing Suppression
  • Euphoria
  • Compulsive Redosing
  • Disinhibition
  • Dulled Perception
  • Blurred Vision
  • Decreased Libido
  • Environmental Transfiguration
  • Morphing

Routes of Administration

Oral

Dosage

  • Heavy: 6 mg
  • Light: 1 – 2 mg
  • Common: 2 – 4 mg
  • Strong: 4 – 6 mg
  • Threshold: < 1 mg

Duration

  • Onset: 0.5-1.5 h
  • After Effects: 10-30 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Metizolam - DrugsPRO ainejuhend

Metizolam: Metizolam is a synthetic depressant of the thienotriazolodiazepine class and the demethylated analogue of etizolam. A Japanese company patented it in 1995 as a possible anxiolytic, but it saw little to no human use before appearing as a grey-area research chemical in September 2015. Compa

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