25I-NBMD is a synthetic psychedelic of the substituted phenethylamine class, specifically an N-benzylated derivative of 2C-I. It was discovered in 2006 by a research team led by David Nichols at Purdue University. Closely related to the 25X-NBOMe series, it is a highly potent compound that acts as a partial agonist at the 5-HT2A receptor. As a research chemical, it has very limited documentation regarding its effects and safety profile in humans.
Also known as: Cimbi-29, Nbmd-2c-i, 2C-I-NBMD, INBMDO, 25I-NB34MD, 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(3,4-methylenedioxyphenyl) methyl]ethanamine
Classification
Chemical: Phenethylamine
Psychoactive: Psychedelic
Tag: Hallucinogen
Tag: N-benzylphenethylamine
Tag: Research-Chemical
Tag: Tentative
Effects
Physical Discomfort
Jaw Tension
Tingling
Physical Comfort
Coldness
Numbness
Time Dilation
Euphoria
Thought Loop
Revelatory Insight
Anxiety
Introspection
Closed Eye Visuals
Open Eye Visuals
Geometric Imagery
Color Enhancement
Pareidolia
Morphing
Routes of Administration
Sublingual
Dosage
Heavy: 800 ug
Light: 800 – 1 200 µg
Common: 800 ug
Strong: 1 800 – 2 500 µg
Threshold: 300 – 600 µg
Duration
Onset: 0.33-0.67 h
After Effects: 1-8 h
Peak: 1-3 h
Offset: 3-7 h
Total Duration: 4-10 h
Buccal
Dosage
Heavy: 800 ug
Light: 800 – 1 200 µg
Common: 800 ug
Strong: 1 800 – 2 500 µg
Threshold: 300 – 600 µg
Duration
No data available for this section yet.
Insufflated
Dosage
Heavy: 600 ug
Light: 300 – 600 µg
Common: 600 – 1 000 µg
Strong: 600 ug
Threshold: 150 – 300 µg
Duration
Onset: 0-0.17 h
Peak: 0.5-2 h
Offset: 2-6 h
After Effects: 0-8 h
Total Duration: 3-8 h
Oral
Dosage
Threshold: unreliable; avoid as primary ROA mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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25I-NBMD - DrugsPRO aineopas
25I-NBMD: 25I-NBMD is a synthetic psychedelic of the substituted phenethylamine class, specifically an N-benzylated derivative of 2C-I. It was discovered in 2006 by a research team led by David Nichols at Purdue University. Closely related to the 25X-NBOMe series, it is a highly potent compound that
