Ibogaine

Ibogaine is a naturally occurring indole alkaloid primarily derived from the root bark of Tabernanthe iboga, a plant native to Central and West Africa. It has been used for centuries within the Bwiti religion of Gabon for initiation rites and spiritual communion. Ibogaine produces psychedelic and dissociative effects often described as dream-like and frequently unpleasant. Since the late 20th century, it has gained significant attention as an experimental treatment for opioid dependence, with clinics established worldwide.

Also known as: Iboga, Endabuse, Nih 10567, 12-methoxyibogamine, T. iboga root bark, Ibogamine-class indole alkaloid

Classification

Chemical: Medicine
Chemical: Opioid
Chemical: Tryptamine
Psychoactive: Depressant
Psychoactive: Dissociative
Tag: Alkaloid
Tag: Ibogalog
Tag: Plant-based
Tag: substituted tryptamine

Effects

Spontaneous Bodily Sensations
Stimulation
Increased Heart Rate
Nausea
Headache
Muscle Tension
Introspection
Analysis Enhancement
Euphoria
Empathy Enhancement
Anxiety
Irritability
Cognitive Dysphoria
Perception Of Bodily Lightness
Dehydration
Appetite Suppression
Auditory Distortion
Auditory Enhancement

Routes of Administration

Oral

Dosage

Heavy: 22 mg/kg
Light: 8 – 12 mg/kg
Common: 12 – 16 mg/kg
Strong: 16 – 22 mg/kg
Threshold: 8 mg/kg

Duration

Onset: 0.75-3 h
Peak: 18-36 h
After Effects: 24-168 h
Offset: 8-24 h
Total Duration: 12-36 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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