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Lean

Lean, also called purple drank or sizzurp, is a non-standard mixture usually made from codeine and promethazine cough syrup. Codeine is an opioid that is partly converted to morphine, while promethazine adds sedative and anticholinergic effects; product strength and individual codeine metabolism can therefore make effects unusually unpredictable. The combination can cause profound drowsiness and respiratory depression, and mixing it with alcohol, benzodiazepines, other opioids, gabapentinoids, GHB/GBL, barbiturates, or other sedatives greatly increases overdose risk.

Also known as: Purple drank, Syrup, Sizzurp, Drank, Barre, Texas tea, Wock

Classification

  • Chemical: Opioid
  • Psychoactive: Depressant
  • Tag: Antihistamine
  • Tag: Habit-Forming
  • Tag: Mixture

Effects

  • Muscle Relaxation
  • Sedation
  • Itching
  • Dry Mouth
  • Incoordination
  • Nausea
  • Euphoria
  • Drowsiness
  • Thought Slowing
  • Reduced Anxiety
  • Anxiety Suppression
  • Confusion
  • Dulled Perception
  • Blurred Vision
  • Auditory Hallucination
  • Cognitive Dysphoria
  • Perception Of Bodily Heaviness
  • Auditory Distortion

Routes of Administration

Oral

Dosage

  • Heavy: 90 mL+ (≥3 oz; strongly discouraged)
  • Light: 10–20 mL
  • Common: 20–60 mL (≈1–2 oz)
  • Strong: 60–90 mL (≈2–3 oz)
  • Threshold: 5–10 mL (½–1 teaspoon)

Duration

  • Onset: 0.25-1 h
  • Peak: 1-2 h
  • Offset: 2-4 h
  • After Effects: 4-12 h
  • Total Duration: 3-6 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

No external data sources listed for this substance yet.

Links

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Lean - DrugsPRO aineopas

Lean: Lean, also called purple drank or sizzurp, is a non-standard mixture usually made from codeine and promethazine cough syrup. Codeine is an opioid that is partly converted to morphine, while promethazine adds sedative and anticholinergic effects; product strength and individual codeine metaboli

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