Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species, such as the potentially deadly C. dealbata. Mushrooms in the genera Entoloma and Mycena have also been found to contain varying levels of muscarine which can be dangerous if ingested. Muscarine has been found in harmless trace amounts in the edible genera Boletus, Hygrocybe, Lactarius and Russula. Trace concentrations of muscarine are also found in preparations of Amanita muscaria, though the more relevant neuroactive compound in this context is the gabaergic alkaloid muscimol. A. muscaria fruitbodies contain a variable but low dose of muscarine, usually around 0.0003% of total fresh weight. Highly toxic Inocybe and Clitocybe species contain muscarine concentrations up to 1.6%.
Muskariini molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Tryptamine
Psychoactive: Psychedelic
Tag: Plant-based
Effects
Dilated Pupils
Nausea
Pupil Dilation
Sedation
Physical Euphoria
Stimulation
Introspection
Anxiety
Analysis Enhancement
Unity And Interconnectedness
Memory Suppression
Euphoria
Visual Distortions
Color Enhancement
Drifting
Auditory Distortion
Internal Hallucination
Routes of Administration
No route information available yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Muscarine - DrugsPRO aineopas
Muscarine: Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species, such as the potentially deadly C. dealbata. Mushrooms in the genera Entoloma and Mycena have also been found to contain varying levels of muscarine which
