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Deschlorokétamine

Deschloroketamine is a dissociative research chemical of the arylcyclohexylamine class. Structurally analogous to ketamine but lacking the chlorine substitution on its phenyl ring, it produces dissociative, anesthetic, and hallucinogenic effects. It is reported to be more potent than ketamine with a longer duration of action. The substance is primarily available through online research chemical vendors as a designer drug.

Deschlorokétamine molecular structure
Deschlorokétamine molecular structure diagram from the DrugsPRO substance library.

Also known as: DCK, DXE, O-PCM, 2′-Oxo-PCM

Classification

  • Chemical: Arylcyclohexylamine
  • Psychoactive: Dissociative
  • Tag: Hallucinogen

Effects

  • Creativity Enhancement
  • Muscle Relaxation
  • Tactile Disconnection
  • Spontaneous Tactile Sensations
  • Physical Euphoria
  • Nausea
  • Depersonalization
  • Derealization
  • Consciousness Disconnection
  • Memory Suppression
  • Ego Death
  • Thought Deceleration
  • Disinhibition
  • Tactile Suppression
  • Perception Of Decreased Weight
  • Visual Sliding
  • Decreased Libido
  • Hallucinations

Routes of Administration

Oral

Dosage

  • Heavy: 50+ mg
  • Light: 10 – 20 mg
  • Common: 20 – 30 mg
  • Strong: 30 – 50 mg
  • Threshold: 10 mg

Duration

  • Onset: 0.17-0.5 h
  • Comeup: 0.5-1 h
  • Peak: 1.5-2.5 h
  • Offset: 2.5-4 h
  • After Effects: 3-24 h
  • Total Duration: 3-6 h

Insufflated

Dosage

  • Heavy: 40+ mg
  • Light: 10 – 15 mg
  • Common: 15 – 25 mg
  • Strong: 25 – 40 mg
  • Threshold: 5 mg

Duration

  • Onset: 0.08-0.33 h
  • Comeup: 0.5-1 h
  • Peak: 1.5-2.5 h
  • Offset: 1.5-3 h
  • After Effects: 3-24 h
  • Total Duration: 1.5-4 h

Smoked

Dosage

  • Threshold: 5 mg
  • Heavy: 40+ mg
  • Common: 10 – 20 mg
  • Light: 5 – 10 mg
  • Strong: 20 – 40 mg

Duration

  • Onset: 0-0.05 h
  • Peak: 0.1-0.5 h
  • Offset: 0.5-1 h
  • After Effects: 1-12 h
  • Total Duration: 0.5-1.5 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Deschloroketamine - Guide des substances DrugsPRO

Deschloroketamine: Deschloroketamine is a dissociative research chemical of the arylcyclohexylamine class. Structurally analogous to ketamine but lacking the chlorine substitution on its phenyl ring, it produces dissociative, anesthetic, and hallucinogenic effects. It is reported to be more potent t

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