Desoxypipradrol is a benzylpiperidine-based stimulant structurally related to methylphenidate and pipradrol. Developed by Ciba in the 1950s for conditions such as narcolepsy and ADHD, it was ultimately abandoned in favor of methylphenidate. It acts as a norepinephrine-dopamine reuptake inhibitor and is distinguished by its exceptionally long duration of action, a consequence of its high lipophilicity which renders it resistant to metabolic breakdown. It resurfaced as a recreational substance in the late 2000s.
Désoxypipradrol molecular structure diagram from the DrugsPRO substance library.
Also known as: Pippy, 2-dpmp, Ivory wave, Vanillasky, Purple wave, 2‑diphenylmethylpiperidine, 2‑desoxypiperadol
Classification
Psychoactive: Stimulant
Tag: Benzylpiperidine
Tag: Habit-Forming
Tag: Pipradrol homologue
Tag: Research-Chemical
Tag: substituted piperidine
Tag: Tentative
Effects
Stimulation
Increased Heart Rate
Increased Perspiration
Bruxism
Itchiness
Muscle Spasms
Euphoria
Anxiety
Irritability
Paranoia
Sociability Enhancement
Wakefulness
Increased Libido
Appetite Suppression
Auditory Hallucination
External Hallucination
Increased Sexuality
Visual And Auditory Hallucinations
Routes of Administration
Insufflated
Dosage
Heavy: 5+ mg
Light: 2 mg
Common: 1.5 – 3.5 mg
Strong: 3.5 – 5 mg
Threshold: 1-2 mg
Duration
Onset: 0.33-1 h
Comeup: 2-6 h
Peak: 6-30 h
Offset: 6-40 h
After Effects: 1-72 h
Oral
Dosage
Heavy: 8+ mg
Light: 0.25 – 2 mg
Common: 2 – 6 mg
Strong: 6 – 8 mg
Threshold: 1-2 mg
Duration
Onset: 1-2 h
Peak: 9-30 h
Offset: 12-36 h
After Effects: 24-72 h
Total Duration: 16-72 h
Oral & Intranasal
Dosage
Heavy: 8 mg
Light: 2 – 3 mg
Common: 4 – 6 mg
Strong: 7 – 8 mg
Threshold: 2 mg
Duration
Onset: 1-2 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Desoxypipradrol - Guide des substances DrugsPRO
Desoxypipradrol: Desoxypipradrol is a benzylpiperidine-based stimulant structurally related to methylphenidate and pipradrol. Developed by Ciba in the 1950s for conditions such as narcolepsy and ADHD, it was ultimately abandoned in favor of methylphenidate. It acts as a norepinephrine-dopamine reupt
