Fluclotizolam is a novel thienotriazolodiazepine research chemical structurally derived from etizolam. It functions as a depressant and anxiolytic through GABAergic activity. Reports suggest it is roughly three times more potent than etizolam with a comparatively shorter duration of action, though dosage information remains inconsistent and poorly established. As with other designer benzodiazepines, it carries significant risks of dependence, and its limited research history means its safety profile is not well characterized.
Fluclotizolam molecular structure diagram from the DrugsPRO substance library.
Also known as: Fluclo
Classification
Chemical: Benzodiazepine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: GABAergic
Tag: Habit-Forming
Tag: Muscle Relaxant
Tag: Research-Chemical
Tag: Sedative
Tag: Tentative
Tag: Thienotriazolodiazepine
Effects
Sedation
Muscle Relaxation
Incoordination
Motor Impairment
Respiratory Depression
Anxiolytic
Anxiety Suppression
Amnesia
Thought Deceleration
Memory Impairment
Delusional Thinking
Euphoria
Disinhibition
Dulled Perception
External Hallucination
Blurred Vision
Decreased Libido
Environmental Transfiguration
Routes of Administration
Oral
Dosage
Heavy: 750 ug
Light: 100 – 250 µg
Common: 250 – 500 µg
Strong: 500 – 750 µg
Threshold: 100 ug
Duration
Onset: 0.17-0.5 h
After Effects: 1-14 h
Peak: 1-3 h
Offset: 3-6 h
Total Duration: 4-8 h
Sublingual
Dosage
Heavy: 0.75mg+ mg
Light: 0.1mg - 0.25mg mg
Common: 0.25mg - 0.5mg mg
Strong: 0.5mg - 0.75mg mg
Threshold: 0.05 mg
Duration
Onset: 0.17-0.5 h
Peak: 1-3 h
Offset: 3-6 h
After Effects: 6-36 h
Total Duration: 4-8 h
Insufflated
Dosage
Heavy: 0.6mg+ mg
Light: 0.05mg - 0.2mg mg
Common: 0.2mg - 0.4mg mg
Strong: 0.4mg - 0.6mg mg
Threshold: 0.05 mg
Duration
Onset: 0.08-0.25 h
Peak: 0.75-2 h
Offset: 2-4 h
After Effects: 4-24 h
Total Duration: 3-6 h
Rectal
Dosage
Heavy: 0.6mg+ mg
Light: 0.1mg - 0.25mg mg
Common: 0.25mg - 0.4mg mg
Strong: 0.4mg - 0.6mg mg
Threshold: 0.1 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Fluclotizolam - Guide des substances DrugsPRO
Fluclotizolam: Fluclotizolam is a novel thienotriazolodiazepine research chemical structurally derived from etizolam. It functions as a depressant and anxiolytic through GABAergic activity. Reports suggest it is roughly three times more potent than etizolam with a comparatively shorter duration of a
